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patients in both groups (83% in Group 1 vs. 70%
              P26                                                 in  Group  2).  Tuberculosis  sequelae  were  the
                                                                  predominant  etiology in  Group  1,  while post-
              ASSESSING THE IMPACT OF                             infectious sequelae were the main etiology in
              INHALED CORTICOSTEROIDS ON                          Group 2. Other etiologies included connective
              EXACERBATION FREQUENCY IN                           tissue disorders (13.3% vs. 0%), ciliary dyskinesia
                                                                  (10% vs. 3.3%), and Kartagener syndrome, which
              BRONCHIECTASIS: A                                   was only found in Group 2. Immunodeficiency
              COMPARATIVE ANALYSIS.                               and cystic fibrosis each accounted for 3.3% in
                                                                  both  groups.  Pseudomonas  aeruginosa
                 O. BEN LAKHAL1, C.JNEYEH, A.FRADI, M.KLILA, J.ELGHOUL   colonization was found in 16.7% of Group 1 vs.

                 HOPITAL HABIB BOURGUIBA MEDENINE1                13.3% of Group 2 (p=0.1). In Group 1, the average
                                                                  number      o     exacerbation       requiring
              Introduction:                                       hospitalization  in  pulmonology  per  year  was

              Bronchiectasis  (DDB)  is  a  chronic  pulmonary    1.27 vs. 1.07 in Group 2 (p=0,08). In Group 1, the
              condition characterized by abnormal bronchial       percentage of patients requiring non-invasive
              dilation,  often  associated  with  recurrent       ventilation (NIV) and admission to an intensive
              inflammation  and  infection  of  the  airways.     care unit (ICU) were 13.3% and 10%, respectively
              Inhaled corticosteroids are commonly used to        (p = 0.6).
              manage  inflammation  in  various  chronic  lung    Conclusion :
              diseases,  but  their  effectiveness  in  reducing
              exacerbations  in  patients  with  bronchiectasis   Our     finding    suggest     that   inhaled
              remains a topic of ongoing debate.                  corticosteroids does not impact  the number of
                                                                  exacerbations in patients with bronchiectasis .
              Objective:
                                                                  The  use  of  inhaled  corticosteroids  should  be
              This  study  investigates  the  impact  of  inhaled   individualized    and    integrated    into    a
              corticosteroid    on    th    frequency    o        comprehensive disease management strategy.
              exacerbations in patients with bronchiectasis.      Additional research is needed to clarify optimal

              Methods:                                            use conditions and to identify which patients
                                                                  may derive the most benefit from this treatment.
              Analytical  study  involving  60  patients  who
              were  hospitalized  in  the  pulmonology
              department  of  Habib  Bourguiba  hospital  ,
              Medenine  between  2014  and    2024.  Two
              groups were compared: Group 1 (G1) consisting
              o     30     patient    receiving     inhaled
              corticosteroids, and Group 2 (G2) consisting of
              30    patient     not    receiving    inhaled
              corticosteroids.

              Result:

              The  two  groups  were  similar  in  terms  of  age,
              sex,  Neffa  and  tobacco consumption. We
              found a higher prevalence of asthma in Group 1
              (56%  vs.  10%)  and  more  patients  with  chronic
              respiratory  failure  (43.3%  vs.  16.7%).  Bilateral
              bronchiectasis was observed in the majority of




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